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MYP_143339
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
33 amino acids
C142H253N41O44S4
Standard
Sequence
GIMDTLKNLAKTAGKGALQSLVKMASCKLSGQC
Physicochemical Analysis
3367.04 Da
9.60
3.74
3.50
0.1132
0.15
0.66
0.08
33.24
91.82
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1392.34
-16.92
50.0
52.0
121.0
231.0
0.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0126578 VERIFIED: YES
Provenance & Taxonomy
Rana esculenta [Animal]
Brevinin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus megaterium BmII
0.2 μM
MIC
PMID8163497 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8163497/
RECORD: Rec_0138685 VERIFIED: YES
Provenance & Taxonomy
Rana esculenta [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human erythrocytes
100 μM
LC50
PMID8163497 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8163497/
RECORD: Rec_0164476 VERIFIED: YES
Provenance & Taxonomy
Rana esculenta [Animal]
Brevinin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Red Blood cells
100 μg/mL
Hemolysis
PMID8163497 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8163497/
RECORD: Rec_0193772 VERIFIED: YES
Provenance & Taxonomy
Pelophylax ridibundus [Animal]
Brevinin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
27-33
Bio-Activity Profile
Antimicrobial Antibacterial
Evidence URLhttps://www.uniprot.org/uniprotkb/P86153/entry
RECORD: Rec_0211450 VERIFIED: YES
Provenance & Taxonomy
Rana esculenta [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID8163497 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8163497/
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