Peptide Database

Peptide NameNatriuretic peptides B

Function Ontology

Cardiovascular

Hormonal / Endocrine ▸ Hormone peptide

Standard StatusStandard

Sequence Length108 amino acids

Chemical FormulaC507H840N164O157S5

DescriptionStandard

        HPLGSPGSASDLETSGLQEQRNHLQGKLSELQVEQTSLEPLQESPRPTGVWKSREVATEGIRGHRKMVLYTLRAPRSPKMVQGSGCFGRKMDRISSSSGLGCKVLRRH
    

Molecular Weight11905.42 Da

Isoelectric Point (pI)10.12

Net Charge (pH 7.0)7.11

Net Charge (pH 7.4) 6.65

Charge Density (pH 7.0) 0.0658

GRAVY Index-0.77

Hydrophobic Moment 0.71

Boman Index-0.19

Instability Index75.51

Aliphatic Index 69.44

Aromaticity 0.0278

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5205.34

LogP -65.00

H-bond Donors 186.0

H-bond Acceptors 173.0

Rotatable Bonds 405.0

Heavy Atoms 833.0

Ring Count 15.0

Amide Bonds 115.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0120017 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyNatriuretic peptide

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide86-102

Bio-Activity Profile

Function

Hormone Cardiovascular