Peptide Database

Peptide NameEpidermal growth factor

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic

Standard StatusStandard

Sequence Length53 amino acids

Chemical FormulaC257H381N73O83S7

DescriptionStandard

        NSYPGCPSSYDGYCLNGGVCMHIESLDSYTCNCVIGYSGDRCQTRDLRWWELR
    

Molecular Weight6045.67 Da

Isoelectric Point (pI)4.89

Net Charge (pH 7.0)-2.21

Net Charge (pH 7.4) -2.56

Charge Density (pH 7.0) -0.0416

GRAVY Index-0.51

Hydrophobic Moment 0.61

Boman Index-0.05

Instability Index79.90

Aliphatic Index 55.09

Aromaticity 0.1321

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2525.95

LogP -29.23

H-bond Donors 96.0

H-bond Acceptors 89.0

Rotatable Bonds 189.0

Heavy Atoms 420.0

Ring Count 12.0

Amide Bonds 56.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0153878 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

Tax ID10090; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-20; 14-31; 33-42

Bio-Activity Profile

Function

Cytokine Growth factor Growth factor signaling Angiogenic