Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length53 amino acids

Chemical FormulaC251H406N74O77S5

DescriptionStandard

        MATKDFNLDLVEVSKSNTGASTRITSHSFCSQACKTYKILGCNLLTHGCRFPR
    

Molecular Weight5852.68 Da

Isoelectric Point (pI)9.16

Net Charge (pH 7.0)3.64

Net Charge (pH 7.4) 3.25

Charge Density (pH 7.0) 0.0686

GRAVY Index-0.21

Hydrophobic Moment 0.68

Boman Index-0.04

Instability Index20.12

Aliphatic Index 68.11

Aromaticity 0.0755

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2462.12

LogP -30.97

H-bond Donors 92.0

H-bond Acceptors 88.0

Rotatable Bonds 195.0

Heavy Atoms 407.0

Ring Count 7.0

Amide Bonds 56.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0351520 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus salivarius [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence