Peptide Database

Peptide NameCXCL17

Function Ontology

Immunology ▸ Immune cell migration ▸ Chemotactic peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length98 amino acids

Chemical FormulaC496H797N173O131S7

DescriptionStandard

        SSLNPGVARGHRDRGQASRRWLQEGGQECECKDWFLRAPRRKFMTVSGLPKKQCPCDHFKGNVKKTRHQRHHRKPNKHSRACQQFLKQCQLRSFALPL
    

Molecular Weight11504.17 Da

Isoelectric Point (pI)10.95

Net Charge (pH 7.0)16.93

Net Charge (pH 7.4) 16.31

Charge Density (pH 7.0) 0.1727

GRAVY Index-1.20

Hydrophobic Moment 0.68

Boman Index-0.38

Instability Index73.20

Aliphatic Index 45.82

Aromaticity 0.0714

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5004.56

LogP -57.43

H-bond Donors 182.0

H-bond Acceptors 161.0

Rotatable Bonds 391.0

Heavy Atoms 807.0

Ring Count 21.0

Amide Bonds 109.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0329786 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidereported in GtoPdb PTM annotation

Other ModsDisulphide bond formation between cysteine residues at positions 28 and 53, and 30 and 55.

Bio-Activity Profile

Function

Receptor agonist Chemotactic Immunomodulatory Signaling peptide

TargetGPR35 (Human); ACKR5 (None)