Peptide Database

Peptide NameNaegleriapore B

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antiparasitic ▸ Antiprotozoal

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC377H616N92O114S7

DescriptionStandard

        SVIGCEICEWLVATAEGFVNKTKPQIEQELLQICAKLGPYEQICDQLVLMELPDIIDQIIAKEPPAIVCSQVKICNG
    

Molecular Weight8485.93 Da

Isoelectric Point (pI)4.29

Net Charge (pH 7.0)-6.58

Net Charge (pH 7.4) -6.90

Charge Density (pH 7.0) -0.0854

GRAVY Index0.33

Hydrophobic Moment 0.57

Boman Index0.20

Instability Index40.50

Aliphatic Index 120.26

Aromaticity 0.0390

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3276.12

LogP -24.25

H-bond Donors 110.0

H-bond Acceptors 115.0

Rotatable Bonds 284.0

Heavy Atoms 590.0

Ring Count 9.0

Amide Bonds 85.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0275236 VERIFIED: YES

Provenance & Taxonomy

OrganismNaegleria fowleri [Protist]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideDisulfide bond(s) reported

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antiprotozoal Cytotoxic

TargetEscherichia coli K-12 D31

RECORD: Rec_0390096 VERIFIED: YES