Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC560H883N149O169S3

DescriptionStandard

        ADLNGYEKFGLGNVKYNISRIHITDVEFPSASISLIPGTGIKLVIGNASLTFTMNWNIRTWMFKDSGRSTVYISKVFVTAIFSTPLHNTDHTSVSLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12503.09 Da

Isoelectric Point (pI)9.21

Net Charge (pH 7.0)3.05

Net Charge (pH 7.4) 2.67

Charge Density (pH 7.0) 0.0268

GRAVY Index-0.01

Hydrophobic Moment 0.53

Boman Index0.11

Instability Index22.51

Aliphatic Index 89.74

Aromaticity 0.0965

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5122.63

LogP -56.56

H-bond Donors 183.0

H-bond Acceptors 178.0

Rotatable Bonds 411.0

Heavy Atoms 881.0

Ring Count 19.0

Amide Bonds 121.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0031091 VERIFIED: NO

Provenance & Taxonomy

OrganismGalbula dea [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria