MYP_143160
Basic Information
Stripe-based foldamer peptide 2
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-negative
Antimicrobial Antibacterial Anti-Gram-positive
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
not Standard
21 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KLLKKXGKLLKKXGKLLKKXG
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0002126 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
The X (position: 6, 13 and 20) in sequence denote Aib residue
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa NBRC13275
1.56 μM
MIC
RECORD: Rec_0010343 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
The Z (position: 6, 13 and 20) in sequence denote Ac₆c residue (1-Aminocyclohexanecarboxylic acid)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli DH5α
3.125 μM
MIC
RECORD: Rec_0010705 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
The X (position: 6, 13 and 20) in sequence denote Aib residue
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
multidrug-resistant Pseudomonas aeruginosa ATCCBAA-2111 (MDRP)
1.56 μM
MIC
RECORD: Rec_0033927 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
The Z (position: 6, 13 and 20) in sequence denote Ac₆c residue (1-Aminocyclohexanecarboxylic acid)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa NBRC13275
6.25 μM
MIC
RECORD: Rec_0045884 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
The Z (position: 6, 13 and 20) in sequence denote Ac₆c residue (1-Aminocyclohexanecarboxylic acid)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Gram-positive bacteria: Staphylococcus aureus NBRC13276
6.25 μM
MIC
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