Peptide Database

Peptide Namecycloviolacin O8

Function Ontology

Antiparasitic ▸ Anthelminthic

Antiparasitic ▸ Anthelminthic ▸ Nematicidal activity

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC135H219N35O41S5

DescriptionStandard

        GTLPGESCVWIPCLSSVVGCSCKSKVCYKN
    

Molecular Weight3148.72 Da

Isoelectric Point (pI)8.40

Net Charge (pH 7.0)1.71

Net Charge (pH 7.4) 1.43

Charge Density (pH 7.0) 0.0570

GRAVY Index0.38

Hydrophobic Moment 0.32

Boman Index0.17

Instability Index40.09

Aliphatic Index 77.67

Aromaticity 0.0667

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7240.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1205.49

LogP -14.08

H-bond Donors 47.0

H-bond Acceptors 48.0

Rotatable Bonds 99.0

Heavy Atoms 216.0

Ring Count 5.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0073531 VERIFIED: YES

Provenance & Taxonomy

OrganismViola odorata [Plant]

FamilyCyclotide

Tax ID97441

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Nematocidal Anthelmintic

TargetTrichostrongylus colubriformis

Activity0.22

MethodIC50

RECORD: Rec_0148873 VERIFIED: YES