Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length105 amino acids

Chemical FormulaC518H816N154O148S13

DescriptionStandard

        MAPSCQLSRDHHASLQRESSQRLPSETTLSRKMSYFVFAFFFILAQFLSGCQAGLEYSEPLPGGEFAACEPCRLGRGKCRRMCTEDEKVVGNCKMNFFCCRRKIR
    

Molecular Weight11985.81 Da

Isoelectric Point (pI)8.98

Net Charge (pH 7.0)5.60

Net Charge (pH 7.4) 5.13

Charge Density (pH 7.0) 0.0534

GRAVY Index-0.33

Hydrophobic Moment 0.60

Boman Index-0.11

Instability Index68.09

Aliphatic Index 55.81

Aromaticity 0.1048

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4892.21

LogP -52.67

H-bond Donors 182.0

H-bond Acceptors 169.0

Rotatable Bonds 400.0

Heavy Atoms 833.0

Ring Count 18.0

Amide Bonds 111.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0115237 VERIFIED: NO

Provenance & Taxonomy

OrganismCallorhinus ursinus [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence