Peptide Database

Peptide NameColicin-E2 (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length142 amino acids

Chemical FormulaC699H1109N209O205S3

DescriptionStandard

        MEPVYVVLSSPRDMPGKVSGNGQQVGDGWLNKAGQELGAPIPSQIADKLRGREFVNFGAFRKAFWTEVGKDHELNKQFKSGNLGNIQAGKAPATRDKEQVGGRVKYELHHMKPIKNNGEVYNVDNISVTTPKRHIEIHREVK
    

Molecular Weight15816.76 Da

Isoelectric Point (pI)9.62

Net Charge (pH 7.0)5.95

Net Charge (pH 7.4) 5.44

Charge Density (pH 7.0) 0.0419

GRAVY Index-0.76

Hydrophobic Moment 0.52

Boman Index-0.11

Instability Index36.51

Aliphatic Index 70.63

Aromaticity 0.0704

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6722.88

LogP -70.67

H-bond Donors 226.0

H-bond Acceptors 219.0

Rotatable Bonds 536.0

Heavy Atoms 1116.0

Ring Count 25.0

Amide Bonds 158.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0113731 VERIFIED: NO

Provenance & Taxonomy

OrganismSerratia rubidaea [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal