Peptide Database

Peptide NameBeta-defensin 105A

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC401H623N107O111S9

DescriptionStandard

        MALIRKTFYFLFAVFFVLVQLPSECQAGLDFSQPFPSDEFAVCESCKLGRGKCRKECLENEKPDGNCRLNFLCCRERI
    

Molecular Weight9007.47 Da

Isoelectric Point (pI)7.48

Net Charge (pH 7.0)0.44

Net Charge (pH 7.4) 0.08

Charge Density (pH 7.0) 0.0056

GRAVY Index-0.02

Hydrophobic Moment 0.46

Boman Index-0.01

Instability Index46.84

Aliphatic Index 75.00

Aromaticity 0.1282

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3523.28

LogP -29.71

H-bond Donors 128.0

H-bond Acceptors 121.0

Rotatable Bonds 299.0

Heavy Atoms 628.0

Ring Count 14.0

Amide Bonds 83.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0211207 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo pygmaeus [Animal]

FamilyDefensin

Tax ID9600

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence