Peptide Database

Peptide NamePeptide 14

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC111H192N32O23S

DescriptionStandard

        FMKKIVKIGKIARYSHKAKK
    

Molecular Weight2374.98 Da

Isoelectric Point (pI)10.82

Net Charge (pH 7.0)7.84

Net Charge (pH 7.4) 7.57

Charge Density (pH 7.0) 0.3920

GRAVY Index-0.57

Hydrophobic Moment 0.68

Boman Index-0.23

Instability Index-5.09

Aliphatic Index 83.00

Aromaticity 0.1000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 929.40

LogP -4.86

H-bond Donors 34.0

H-bond Acceptors 33.0

Rotatable Bonds 88.0

Heavy Atoms 167.0

Ring Count 3.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0409446 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus

Activity128 μM

MethodMBC

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