Peptide Database

Peptide NameBrevinin-1PLc

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC364H589N91O104S6

DescriptionStandard

        MFTLKKSMLLLFFLGTINLSLCEEERNAEEERRDEPDEMDVEVEKRFLPVIAGVAAKFLPKIFCAITKKC
    

Molecular Weight8096.51 Da

Isoelectric Point (pI)5.12

Net Charge (pH 7.0)-2.50

Net Charge (pH 7.4) -2.79

Charge Density (pH 7.0) -0.0358

GRAVY Index0.01

Hydrophobic Moment 0.60

Boman Index0.01

Instability Index49.38

Aliphatic Index 96.14

Aromaticity 0.0857

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3146.82

LogP -20.64

H-bond Donors 110.0

H-bond Acceptors 108.0

Rotatable Bonds 279.0

Heavy Atoms 565.0

Ring Count 9.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0061877 VERIFIED: YES

Provenance & Taxonomy

OrganismLithobates palustris [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetEscherichia coli

RECORD: Rec_0262699 VERIFIED: YES