MYP_142923
Achromonodin-1
Antimicrobial
Standard
30 amino acids
C148H216N36O43S
Standard
GGGGPTPEYFLMPIDPAWLQANLPNTGKYN
3219.58 Da
4.37
-1.24
-1.45
-0.0413
-0.52
0.33
0.18
61.78
58.67
0.1333
8480.00
8480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1232.96
-10.89
38.0
43.0
93.0
228.0
10.0
33.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0412290
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Achromonodin-1 is naturally encoded by certain isolates from the sputum of patients with cystic fibrosis. Chemical modification: it forms an eight-membered macrolactam ring between Gly1 and Glu8. Sequence analysis: APD analysis reveals this sequence is most similar (39.39%) to Ubonodin G=P: 17%; L=N: 10%. GRAVY: -0.52; M Wt: 3219.627; Mol formula: C148H220N33O43S1; mol ex coeff: 8530
Bio-Activity Profile
Antimicrobial
A. pulmonis, an isolate from the sputum of a cystic fibrosis patient. Structure: due to limited solubility in water, the peptide was solubilized in CD3OH. NMR studies confirmed the lasso structure