Peptide Database

Peptide NamePDD-B

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC76H131N19O16

DescriptionStandard

        INWLKLGKKILGAL
    

Molecular Weight1566.97 Da

Isoelectric Point (pI)10.30

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.1969

GRAVY Index0.65

Hydrophobic Moment 0.59

Boman Index0.29

Instability Index-5.87

Aliphatic Index 174.29

Aromaticity 0.0714

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 578.56

LogP -0.75

H-bond Donors 20.0

H-bond Acceptors 19.0

Rotatable Bonds 55.0

Heavy Atoms 111.0

Ring Count 2.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0361302 VERIFIED: YES

Provenance & Taxonomy

OrganismPolistes dorsalis [Animal]

FamilyMastoparan

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Hemolytic

Targethuman erythrocytes

Activity45 μM

MethodIC50

RECORD: Rec_0362156 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetBacillus subtilis (

Activity15.5 μM

MethodMIC

RECORD: Rec_0363953 VERIFIED: YES

Provenance & Taxonomy

OrganismPolistes dorsalis [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic

Targetrat red blood cells

Activity45 μM

MethodIC50

RECORD: Rec_0391800 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Toxic Hemolytic Anti-Gram-positive Anti-Gram-negative

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