‹ ›
MYP_142916
← PREVIOUS NEXT → BACK
Basic Information
PDD-B
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
14 amino acids
C76H131N19O16
Standard
Sequence
INWLKLGKKILGAL
Physicochemical Analysis
1566.97 Da
10.30
2.76
2.55
0.1969
0.65
0.59
0.29
-5.87
174.29
0.0714
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
578.56
-0.75
20.0
19.0
55.0
111.0
2.0
14.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0173121 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0177729 VERIFIED: YES
Provenance & Taxonomy
Polistes dorsalis dorsalis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Rat erythrocytes
45 μM
IC50
PaperCerovský V, Slaninová J, Fučík V, et al. New potent antimicrobial peptides from the venom of Polistinae wasps and their analogs. Peptides. 2008 Jun;29(6):992-1003. doi:10.1016/j.peptides.2008.02.007. PMID18375018 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18375018/
RECORD: Rec_0179101 VERIFIED: YES
Provenance & Taxonomy
Polistes dorsalis [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
70 μM
MIC
PMID18375018 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18375018/
RECORD: Rec_0183602 VERIFIED: YES
Provenance & Taxonomy
Polistes dorsalis [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperPeptides. 2008 Jun;29(6):992-1003 | http://www.ncbi.nlm.nih.gov/pubmed/18375018 PMID18375018 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18375018/
RECORD: Rec_0200152 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Polistes dorsalis dorsolis [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Bacillus subtilis
15.5 μM
MIC
PaperNew potent antimicrobial peptides from the venom of Polistinae wasps and their analogs
FIRST PREV 1 2 3 4 NEXT LAST
Showing 5 records on this page · Page 2 of 4