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MYP_142907
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
5 amino acids
C28H43N5O7S
Standard
Sequence
MLPAY
Physicochemical Analysis
593.74 Da
5.27
-0.50
-0.72
-0.1001
0.92
0.21
0.54
85.04
98.00
0.2000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
191.16
0.61
6.0
8.0
15.0
41.0
2.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0052405 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
0.33-5.8 μg/mL
IC50
PaperISOLATION AND CHARACTERIZATION OF PEPTIDES WITH ANTIHYPERTENSIVE ACTIVITY IN FOODSTUFFS. PMID24915368 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24915368/
RECORD: Rec_0075826 VERIFIED: NO
Provenance & Taxonomy
Sesamum indicum [Plant]
ACE-inhibitory peptide
4182
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory Antioxidant
ACE
1.58 μM
IC50
PaperVegetable foods: A cheap source of proteins and peptides with antihypertensive, antioxidant, and other less occurrence bioactivities. PMID23598136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598136/
RECORD: Rec_0094710 VERIFIED: YES
Provenance & Taxonomy
Sesamum indicum [Plant]
ACE inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory Antihypertensive
Angiotensin-converting enzyme
PaperPubMed PMID 16717411 | PubMed PMID 23740810 PMID16717411;23740810 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16717411/
RECORD: Rec_0145953 VERIFIED: YES
Provenance & Taxonomy
Sesamum indicum [Plant]
ACE-inhibitory peptide
4182
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
1.58 μM
IC50
PaperAntihypertensive effect of angiotensin I-converting enzyme inhibitory peptides from a sesame protein hydrolysate in spontaneously hypertensive rats PMID16717411 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16717411/
RECORD: Rec_0255122 VERIFIED: NO
Provenance & Taxonomy
Sesamum indicum [Plant]
ACE-inhibitory peptide
4182
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive Antioxidant
Spontaneously hypertensive rat (SHR)
25 mmHg
SBP decrease
PaperVegetable foods: A cheap source of proteins and peptides with antihypertensive, antioxidant, and other less occurrence bioactivities. PMID23598136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598136/
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