Peptide Database

Peptide NameKininogen-1 (Alpha-2-thiol proteinase inhibitor), (Fitzgerald factor), (High molecular weight kininogen), (HMWK), (Williams-Fitzgerald-Flaujeac factor)

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length644 amino acids

Chemical FormulaC3145H4883N893O993S27

DescriptionStandard

        MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNSQNQSNNQFVLYRITEATKTVGSDTFYSFKYEIKEGDCPVQSGKTWQDCEYKDAAKAATGECTATVGKRSSTKFSVATQTCQITPAEGPVVTAQYDCLGCVHPISTQSPDLEPILRHGIQYFNNNTQHSSLFMLNEVKRAQRQVVAGLNFRITYSIVQTNCSKENFLFLTPDCKSLWNGDTGECTDNAYIDIQLRIASFSQNCDIYPGKDFVQPPTKICVGCPRDIPTNSPELEETLTHTITKLNAENNATFYFKIDNVKKARVQVVAGKKYFIDFVARETTCSKESNEELTESCETKKLGQSLDCNAEVYVVPWEKKIYPTVNCQPLGMISLMKRPPGFSPFRSSRIGEIKEETTVSPPHTSMAPAQDEERDSGKEQGHTRRHDWGHEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDSTTPSAQTQEKTEGPTPIPSLAKPGVTVTFSDFQDSDLIATMMPPISPAPIQSDDDWIPDIQIDPNGLSFNPISDFPDTTSPKCPGRPWKSVSEINPTTQMKESYYFDLTDGLS
    

Molecular Weight71956.56 Da

Isoelectric Point (pI)6.34

Net Charge (pH 7.0)-7.89

Net Charge (pH 7.4) -10.15

Charge Density (pH 7.0) -0.0123

GRAVY Index-0.76

Hydrophobic Moment 0.75

Boman Index-0.09

Instability Index41.07

Aliphatic Index 61.77

Aromaticity 0.0745

Extinction Coeff. Reduced 62340.00

Extinction Coeff. Oxidized 63465.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0182694 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyCystatin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial