Peptide Database

Peptide NameBeta-defensin 1TB

Function Ontology

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Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC163H248N48O50S6

DescriptionStandard

        DHYRCVNNGGTCHYSLCPLFSEVKGTCYNGKAKCC
    

Molecular Weight3872.39 Da

Isoelectric Point (pI)8.31

Net Charge (pH 7.0)1.87

Net Charge (pH 7.4) 1.47

Charge Density (pH 7.0) 0.0535

GRAVY Index-0.42

Hydrophobic Moment 0.50

Boman Index-0.05

Instability Index32.57

Aliphatic Index 41.71

Aromaticity 0.1143

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1586.73

LogP -19.70

H-bond Donors 61.0

H-bond Acceptors 60.0

Rotatable Bonds 123.0

Heavy Atoms 267.0

Ring Count 7.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0287918 VERIFIED: YES

Provenance & Taxonomy

OrganismEchinops telfairi [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)