Peptide Database

Peptide NameSLAY-screened peptide P1633

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC76H121N25O27S

DescriptionStandard

        AQTHETSCQNSIINRF
    

Molecular Weight1848.99 Da

Isoelectric Point (pI)6.78

Net Charge (pH 7.0)-0.12

Net Charge (pH 7.4) -0.38

Charge Density (pH 7.0) -0.0078

GRAVY Index-0.76

Hydrophobic Moment 0.39

Boman Index-0.16

Instability Index25.04

Aliphatic Index 55.00

Aromaticity 0.0625

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 880.98

LogP -12.92

H-bond Donors 31.0

H-bond Acceptors 29.0

Rotatable Bonds 61.0

Heavy Atoms 129.0

Ring Count 2.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0228470 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/