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MYP_142815
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Basic Information
Cathelicidin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
38 amino acids
C199H341N63O56
Standard
Sequence
RLKELITTGGQKIGEKIRRIGQRIKDFFKNLQPREEKS
Physicochemical Analysis
4512.23 Da
10.61
5.77
5.55
0.1517
-1.14
0.92
-0.38
29.21
82.11
0.0526
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2016.40
-19.33
71.0
62.0
166.0
318.0
3.0
41.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0378945 VERIFIED: YES
Provenance & Taxonomy
Canis lupus familiaris [Animal]
Cathelicidin
9615
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-positive Anti-Gram-negative
Proteus mirabilis ATCC 12453
1.11 μM
MIC
PMID17462733 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17462733/
RECORD: Rec_0379249 VERIFIED: YES
Provenance & Taxonomy
Canis lupus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0380556 VERIFIED: YES
Provenance & Taxonomy
Canis lupus familiaris [Animal]
Cathelicidin
9615
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 10832
44.33 μM
MIC
PMID17462733 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17462733/
RECORD: Rec_0390687 VERIFIED: YES
Provenance & Taxonomy
Canis lupus familiaris [Animal]
Cathelicidin
9615
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Ureaplasma canigenitalium ATCC 51252
0.06 μM
MIC
PMID17462733 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17462733/
RECORD: Rec_0390951 VERIFIED: YES
Provenance & Taxonomy
Canis lupus familiaris [Animal]
Cathelicidin
9615
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 700336
1.11 μM
MIC
PMID17462733 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17462733/
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