Peptide Database

Peptide NameBeta-defensin 1TB

Function Ontology

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Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC165H250N46O47S7

DescriptionStandard

        DHYQCVRNGGFCLYSACPMFSKVVGTCYNGKAKCC
    

Molecular Weight3854.48 Da

Isoelectric Point (pI)8.64

Net Charge (pH 7.0)2.78

Net Charge (pH 7.4) 2.43

Charge Density (pH 7.0) 0.0795

GRAVY Index-0.01

Hydrophobic Moment 0.44

Boman Index0.06

Instability Index28.13

Aliphatic Index 41.71

Aromaticity 0.1429

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1500.52

LogP -16.90

H-bond Donors 58.0

H-bond Acceptors 58.0

Rotatable Bonds 122.0

Heavy Atoms 265.0

Ring Count 7.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0334315 VERIFIED: YES

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)