Peptide Database

Peptide NameEumenine mastoparan-EM2)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antiparasitic ▸ Antiprotozoal

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC71H133N17O15

DescriptionStandard

        LKLLGIVKKVLGAI
    

Molecular Weight1464.92 Da

Isoelectric Point (pI)10.30

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.1969

GRAVY Index1.56

Hydrophobic Moment 0.51

Boman Index0.45

Instability Index-29.16

Aliphatic Index 215.71

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 519.68

LogP -0.04

H-bond Donors 18.0

H-bond Acceptors 18.0

Rotatable Bonds 53.0

Heavy Atoms 103.0

Ring Count 0.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0069168 VERIFIED: YES

Provenance & Taxonomy

OrganismEumenes micado [Animal]

FamilyMastoparan

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiparasitic Antiprotozoal Anti-Gram-positive Anti-Gram-negative

TargetLeishmania major

Activity36 μM

MethodIC50

RECORD: Rec_0077147 VERIFIED: YES

Provenance & Taxonomy

OrganismEumenes micado [Animal]

FamilyMastoparan

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hemolytic

TargetMouse erythrocytes [No significant hemolytic activity]

MethodHemolysis

RECORD: Rec_0091075 VERIFIED: YES

Provenance & Taxonomy

OrganismEumenes micado [Animal]

FamilyMastoparan

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiparasitic Antiprotozoal Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus saprophyticus (CS)

Activity3 μM

MethodMIC

RECORD: Rec_0190430 VERIFIED: YES

Provenance & Taxonomy

OrganismEumenes micado [Animal]

FamilyMastoparan

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiparasitic Antiprotozoal Anti-Gram-positive Anti-Gram-negative

TargetEscherichia cloacae ATCC 23355

Activity34 μM

MethodMIC

RECORD: Rec_0221426 VERIFIED: YES

Provenance & Taxonomy

OrganismEumenes micado [Animal]

FamilyMastoparan

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiparasitic Antiprotozoal Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli CCT 1371

Activity34 μM

MethodMIC

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