Peptide Database

Peptide NameColicin pyosin nuclease family protein (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length591 amino acids

Chemical FormulaC2823H4429N739O889S9

DescriptionStandard

        MPMIGDTLYLPEIEINAINKYEPQTFGGGGGDSDFSHSHTGQLINVATRTYILSTYPPIISQNVKDQEASFATNLQSMPESIAKSITAIEQNEGSPASEVEKIEQHIRSVDTLITQKSQAAAAQKAIADKYYYGDFFRFPTMQFIKDAISGSKTNYPPDKNYKEWYTSLEAAYAAKYIIREIDYLNVLKQNLQAQANQARADAEAKRIADEAAAAEAARVAAEAAALKAAHTFRLPAAGAMQLSTAAGSIAVTAGSGVTLEAAIQAAKVALSTVVSAATAVGIGALTYSESLGNGELPATMLDLPAKELAPSLPDNLLEVAAAGGTVDVLYRLYGDQSKYSVVATQVTGGLAPTVPVRALVLDPVANAYTFTTTDTPPITLAFPIAVPGNSSTATPAQPVETPVYTGITLTPIDVKAEPFPIASQLSIRDAIYVYPADSGLPPIYAVFSSPYEGATTKGVHSGRMYNPDKAGGPTQDLDWATATVTQEGIDLVKLHTSRFVPSDANKIMIERLEKILSGQIPVTDVDKRFYTHEMRELERYRALGVADGVEGNVWNNAHAATLEDYKLRDADDLFYTPEAIAAEIKQVYGE
    

Molecular Weight63233.37 Da

Isoelectric Point (pI)4.84

Net Charge (pH 7.0)-22.71

Net Charge (pH 7.4) -23.51

Charge Density (pH 7.0) -0.0384

GRAVY Index-0.13

Hydrophobic Moment 0.71

Boman Index0.10

Instability Index34.75

Aliphatic Index 87.65

Aromaticity 0.0795

Extinction Coeff. Reduced 59710.00

Extinction Coeff. Oxidized 59710.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0103323 VERIFIED: NO

Provenance & Taxonomy

OrganismPseudomonas fluorescens [Bacterium]

FamilyPyocin/Colicin

Tax ID294

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Hydrolase Non-hemolytic Non-ribosomal