Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length228 amino acids

Chemical FormulaC1157H1766N266O340S6

DescriptionStandard

        IDDLAEVDYSLNSLPAVFRPFIDLDLKGIVYPAGNHTGPPYAAAPFTIPVHSDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPVISLVQDSFTVVIQGSMEVFALLPDSTTQSLFTTNITANTSIALNIFDQKLVGSLCLNRLQFSLAHSNVGFFEISLLENILSYILQTEVITSANAKLSRGFPLP
    

Molecular Weight25034.37 Da

Isoelectric Point (pI)4.37

Net Charge (pH 7.0)-11.97

Net Charge (pH 7.4) -12.41

Charge Density (pH 7.0) -0.0525

GRAVY Index0.43

Hydrophobic Moment 0.60

Boman Index0.28

Instability Index45.60

Aliphatic Index 104.39

Aromaticity 0.1272

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0044668 VERIFIED: NO

Provenance & Taxonomy

OrganismUpupa epops [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria