Peptide Database

Peptide NameBombesin

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ Growth inhibitors

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC75H112N26O19

DescriptionStandard

        PYRQRLGNQWAVGH
    

Molecular Weight1681.85 Da

Isoelectric Point (pI)10.84

Net Charge (pH 7.0)2.04

Net Charge (pH 7.4) 1.94

Charge Density (pH 7.0) 0.1461

GRAVY Index-1.25

Hydrophobic Moment 0.36

Boman Index-0.22

Instability Index-17.29

Aliphatic Index 55.71

Aromaticity 0.1429

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 745.40

LogP -7.32

H-bond Donors 27.0

H-bond Acceptors 22.0

Rotatable Bonds 52.0

Heavy Atoms 120.0

Ring Count 5.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0258628 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyBombesin

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermNone

C-TermAmidation

Other ModsPyr=Pyro-glutamine

Bio-Activity Profile

Function

Growth stimulator

Activity0.001 μM

MethodIC50

Half-LifeSCLC cell line NCI-H345, in vitro; 25020 s

RECORD: Rec_0351962 VERIFIED: YES