Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC364H613N111O90S8

DescriptionStandard

        IRIRKKDFLFLGKLCIILTNCFLHLAGGAFRRRKLCAKLNGRCEAECLSFEVKIGGCRAELTQLCCKKKQKH
    

Molecular Weight8240.97 Da

Isoelectric Point (pI)9.82

Net Charge (pH 7.0)11.86

Net Charge (pH 7.4) 11.41

Charge Density (pH 7.0) 0.1647

GRAVY Index-0.02

Hydrophobic Moment 0.56

Boman Index-0.10

Instability Index29.79

Aliphatic Index 97.64

Aromaticity 0.0694

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3299.83

LogP -27.21

H-bond Donors 126.0

H-bond Acceptors 112.0

Rotatable Bonds 293.0

Heavy Atoms 573.0

Ring Count 7.0

Amide Bonds 75.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0200851 VERIFIED: NO

Provenance & Taxonomy

OrganismMarmota marmota marmota [Animal]

FamilyDefensin

Tax ID9994

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal