Peptide Database

Peptide NameCycloviolacin-O8 (Cyclotide c1)

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length118 amino acids

Chemical FormulaC551H898N140O167S10

DescriptionStandard

        MEMKNMVVGLFLIAAFALPALATNFEKDFITHETVQAILKKVGPSSNGMLDEQTISALTGKTIISNPVLEEALLTHSNSINALGGTLPCGESCVWIPCISSVVGCSCKSKVCYKNSLA
    

Molecular Weight12476.51 Da

Isoelectric Point (pI)6.05

Net Charge (pH 7.0)-1.37

Net Charge (pH 7.4) -1.80

Charge Density (pH 7.0) -0.0116

GRAVY Index0.43

Hydrophobic Moment 0.55

Boman Index0.23

Instability Index21.59

Aliphatic Index 103.31

Aromaticity 0.0508

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4853.72

LogP -49.37

H-bond Donors 170.0

H-bond Acceptors 178.0

Rotatable Bonds 414.0

Heavy Atoms 868.0

Ring Count 14.0

Amide Bonds 126.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0013142 VERIFIED: NO

Provenance & Taxonomy

OrganismViola odorata [Plant]

FamilyCyclotide

Structure & Mods

Configbackbone-cyclized cyclotide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0067391 VERIFIED: NO

Provenance & Taxonomy

OrganismViola odorata [Plant]

FamilyCyclotide

Tax ID97441

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

Antimicrobial