Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length223 amino acids

Chemical FormulaC1110H1695N257O348S8

DescriptionStandard

        IDDLAEIDYSLKSLPAVSRPYIDLDLKGVVYPGGNYSAPPFVAAPFTVPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEEVSRTCSYFNISTEIFGSIIPEGAQYSVTPYPVMLKLMATETPIISLQQDSFTLEIQGSMEVFAVLPDSSTQSLFTMSIAANTSISVNTFDQKLMGSLCLNRLQYSLTHSNVGSFEISLLENILSYILQTEVIPSANGE
    

Molecular Weight24464.36 Da

Isoelectric Point (pI)4.06

Net Charge (pH 7.0)-16.14

Net Charge (pH 7.4) -16.48

Charge Density (pH 7.0) -0.0724

GRAVY Index0.21

Hydrophobic Moment 0.56

Boman Index0.22

Instability Index51.29

Aliphatic Index 94.04

Aromaticity 0.1211

Extinction Coeff. Reduced 19370.00

Extinction Coeff. Oxidized 19495.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0002110 VERIFIED: NO

Provenance & Taxonomy

OrganismNothoprocta pentlandii [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria

RECORD: Rec_0186698 VERIFIED: NO