Peptide Database

Peptide NameCycloviolacin O25

Function Ontology

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Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC118H190N30O37S6

DescriptionStandard

        CGESCVFIPCLTAVVGCSCSNKVCYLN
    

Molecular Weight2813.34 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-0.30

Net Charge (pH 7.4) -0.59

Charge Density (pH 7.0) -0.0111

GRAVY Index1.01

Hydrophobic Moment 0.27

Boman Index0.31

Instability Index41.08

Aliphatic Index 90.00

Aromaticity 0.0741

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1061.78

LogP -12.57

H-bond Donors 42.0

H-bond Acceptors 43.0

Rotatable Bonds 87.0

Heavy Atoms 191.0

Ring Count 3.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0420879 VERIFIED: YES

Provenance & Taxonomy

OrganismOldenlandia affinis [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli TOP10

Activity3.82 OD_ID

MethodMeX pooled growth assay (4.5 h; NGS-based growth readout)