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MYP_142497
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Glycosidase inhibition ▸ Alpha-glucosidase inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Lipase inhibition
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
7 amino acids
C33H60N8O10
Standard
Sequence
LAPSTIK
Physicochemical Analysis
728.88 Da
8.75
0.76
0.55
0.1084
0.44
0.42
0.21
51.47
125.71
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
295.61
-2.57
10.0
11.0
22.0
51.0
1.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0004816 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antidiabetic Alpha-glucosidase inhibitory
Alpha-glucosidase
62.55
IC50
PaperZieli¨½ska E., Kara? M., Baraniak B., Jakubczyk A.. Evaluation of ACE, alpha?glucosidase, and lipase inhibitory activities of peptides obtained by in vitro digestion of selected species of edible insects. Eur. Food Res. Technol., 246, 1361-1369, 2020.
RECORD: Rec_0006064 VERIFIED: YES
Provenance & Taxonomy
Gryllodes sigillatus [Animal]
Angiotensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory
alpha-glucosidase
45.60 ± 0.7 μM
IC50
RECORD: Rec_0050539 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Metabolic Syndrome Pancreatic lipase inhibitory
Pancreatic lipase
144.05
IC50
PaperZieli¨½ska E., Kara? M., Baraniak B., Jakubczyk A.. Evaluation of ACE, alpha?glucosidase, and lipase inhibitory activities of peptides obtained by in vitro digestion of selected species of edible insects. Eur. Food Res. Technol., 246, 1361-1369, 2020.
RECORD: Rec_0069277 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
15.29
IC50
PaperZieli¨½ska E., Kara? M., Baraniak B., Jakubczyk A.. Evaluation of ACE, alpha?glucosidase, and lipase inhibitory activities of peptides obtained by in vitro digestion of selected species of edible insects. Eur. Food Res. Technol., 246, 1361-1369, 2020.
RECORD: Rec_0101897 VERIFIED: YES
Provenance & Taxonomy
Gryllodes sigillatus [Animal]
Angiotensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-converting enzyme
11.14 ± 0.08 μg/mL
IC50
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