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MYP_142445
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Basic Information
EB-Lytic
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
32 amino acids
C183H301N45O39
Standard
Sequence
YHWYGYTPQNVIGGGKLLLKLLKKLLKLLKKK
Physicochemical Analysis
3755.63 Da
10.24
7.84
7.57
0.2449
-0.23
0.84
0.05
-5.46
130.94
0.1250
9970.00
9970.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1376.36
-3.34
48.0
48.0
131.0
267.0
7.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0058355 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer
U-251
12 μM
IC50
PaperSelective anticancer chimeric peptide comprising an EGF receptor-binding peptide and a cytotoxic peptide Evidence URLhttps://patents.google.com/patent/US8436137B2/en PatentUS8436137B2
RECORD: Rec_0070585 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
LNCaP
10 μM
IC50
PaperSelective anticancer chimeric peptide comprising an EGF receptor-binding peptide and a cytotoxic peptide Evidence URLhttps://patents.google.com/patent/US8436137B2/en PatentUS8436137B2
RECORD: Rec_0072586 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 21351323 PMID21351323 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21351323/
RECORD: Rec_0109370 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
MDA-MB-231
0.12 μM
IC50
PMID21351323 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21351323/
RECORD: Rec_0154382 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
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