Peptide Database

Peptide NamePancreatic icosapeptide-like

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide Y family

Standard StatusStandard

Sequence Length62 amino acids

Chemical FormulaC271H419N85O82S2

DescriptionStandard

        SAEEDALGLPVWRQSHAAAPGGSHRHPPAGLPAAKGGTGVSGSPPKPWDCLPCRAHSLPSQS
    

Molecular Weight6243.88 Da

Isoelectric Point (pI)7.87

Net Charge (pH 7.0)0.79

Net Charge (pH 7.4) 0.35

Charge Density (pH 7.0) 0.0128

GRAVY Index-0.56

Hydrophobic Moment 0.40

Boman Index0.03

Instability Index81.20

Aliphatic Index 55.32

Aromaticity 0.0323

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2552.01

LogP -33.45

H-bond Donors 87.0

H-bond Acceptors 89.0

Rotatable Bonds 184.0

Heavy Atoms 440.0

Ring Count 18.0

Amide Bonds 63.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0254614 VERIFIED: YES

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyNPY

Tax ID10141

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

NPY-family Neuropeptide Neuromodulator

RECORD: Rec_0269307 VERIFIED: YES

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyPancreatic icosapeptide-like

Tax ID10141

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0273298 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/