MYP_142379
Unnamed
Antimicrobial
Antiviral
▸
Antiviral
▸
Anti-HIV
▸
Antiviral
▸
Antiviral mechanism
▸
Antiviral
▸
Antiviral mechanism
▸
Viral fusion inhibition
▸
Standard
48 amino acids
C257H441N69O72
Standard
IKKEIEAIKKEQEAIKKKIEAIEKEIEAQQHLLQLTVWGIKQLQARIL
5649.67 Da
9.11
1.86
1.58
0.0388
-0.44
0.60
-0.09
76.22
130.21
0.0208
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
2348.74
-13.78
78.0
75.0
211.0
398.0
3.0
53.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0025199
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
HIV-1
RECORD: Rec_0084854
VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
HIV gp41 N-peptide fusion inhibitor
32630.0
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Acetylation
Amidation
Bio-Activity Profile
Anti-HIV
Fusion inhibitor
HIV
RECORD: Rec_0144419
VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0402959
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Anti-HIV-1
Fusion inhibition
HIV-1 | 293T cells; HOS-CD4/fusion cells
0.03±0.01 μM
IC50
Mammalian: 20 h; Yeast: 30 min; E. coli: >10 h