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MYP_142357
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Basic Information
Neuropeptide Y
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Cardiovascular
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide signaling
Neurological / Signaling ▸ Neuropeptide Y family
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Reproductive biology ▸ Reproductive modulation
Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Anti-aging
Standard
36 amino acids
C189H284N54O58S
Standard
Sequence
YPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY
Physicochemical Analysis
4272.67 Da
6.76
-0.15
-0.42
-0.0042
-1.19
0.73
-0.24
63.74
54.44
0.1389
7450.00
7450.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1826.57
-17.54
63.0
60.0
132.0
302.0
10.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0378926 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
S. mutans NCTC 10449, L acidophilus NCTC 1723, Enterococcus faecalis NCTC 12697, Pseudomonas aeruginosa ATCC 27853, and Candida albicans NCTC 3179
125-280 μg/mL
MIC
PaperEnhancement of antimicrobial activity of neuropeptide Y by N-terminal truncation
RECORD: Rec_0381062 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Neuropeptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-aging Immunomodulatory
BALB/c mice (In vivo)
ELISA
PaperNeuropeptide Y effects on murine natural killer activity: changes with ageing and cAMP involvement PMID11495681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11495681/
RECORD: Rec_0381716 VERIFIED: YES
Provenance & Taxonomy
Cavia porcellus [Animal]
Neuropeptide Y
10141
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Reproductive regulator Feeding regulator
Experimental: ~ 20 (20-28) minutes; /1200 seconds; Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Neuropeptide Y (Cavia porcellus): PMID 3368580##3601235 PMID3368580;3601235 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3368580/
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