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MYP_142357
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Basic Information
Neuropeptide Y
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Cardiovascular
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide signaling
Neurological / Signaling ▸ Neuropeptide Y family
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Reproductive biology ▸ Reproductive modulation
Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Anti-aging
Standard
36 amino acids
C189H284N54O58S
Standard
Sequence
YPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY
Physicochemical Analysis
4272.67 Da
6.76
-0.15
-0.42
-0.0042
-1.19
0.73
-0.24
63.74
54.44
0.1389
7450.00
7450.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1826.57
-17.54
63.0
60.0
132.0
302.0
10.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0292185 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
NPY
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
NPY-family Neuropeptide Neuromodulator
PMID3413293 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3413293/
RECORD: Rec_0294268 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Neuropeptide Y
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Neurotransmitter
Radioimmunoassay
Six mongrel dogs plasma (Dose i/v injected), in vivo; ~1200 s
PMID3601235 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3601235/
RECORD: Rec_0306541 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Neuropeptide Y
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
PaperNovel peptide conjugates for tumor-specific chemotherapy Evidence URLhttps://doi.org/10.1021/jm001065f
RECORD: Rec_0310688 VERIFIED: YES
Provenance & Taxonomy
Cricetulus barabensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0323918 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
NPY
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
NPY-family Neuropeptide Neuromodulator
PMID8101369 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8101369/
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