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MYP_142339
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Basic Information
Panurgine R
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
25 amino acids
C123H221N35O29S4
Standard
Sequence
LDVKKIICVACKIRPNPACKKICPK
Physicochemical Analysis
2782.55 Da
9.62
5.72
5.44
0.2286
0.16
0.63
-0.07
52.36
109.20
0.0000
0.00
250.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1033.76
-6.76
38.0
39.0
94.0
191.0
3.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0100274 VERIFIED: YES
Provenance & Taxonomy
Panurgus calcaratus [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID23483218 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23483218/
RECORD: Rec_0120925 VERIFIED: YES
Provenance & Taxonomy
Panurgus calcaratus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans
18.7 μM
MIC
RECORD: Rec_0169463 VERIFIED: YES
Provenance & Taxonomy
Panurgus calcaratus [Animal]
Panurgine
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PaperAmino Acids. 2013 Jul;45(1):143-57. | http://www.ncbi.nlm.nih.gov/pubmed/23483218 PMID23483218 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23483218/
RECORD: Rec_0241565 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0260696 VERIFIED: YES
Provenance & Taxonomy
Communal bee [Animal]; Insecta [Animal]
33208; 50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Paclitaxel conjugation
Bio-Activity Profile
Antimicrobial
PMID23483218 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23483218/
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