Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length178 amino acids

Chemical FormulaC886H1405N245O240S8

DescriptionStandard

        PTVLPEAHEPMLLLAVTDFLANSATFTYFTAGALRRNISSNMLPRRFPLQLRTKSMGLFCPELQERYPDQPMELHLSARRQPLLSCRPDALHGALFGSAEAFVVLPNATRVPAFLLNIDANVTGKPTITGNRLGGTVRLTGGLLPVPQVNRLETLLKFGLWLFGVPWANSECCPRPPP
    

Molecular Weight19585.65 Da

Isoelectric Point (pI)9.45

Net Charge (pH 7.0)5.20

Net Charge (pH 7.4) 4.91

Charge Density (pH 7.0) 0.0292

GRAVY Index0.04

Hydrophobic Moment 0.57

Boman Index0.09

Instability Index56.52

Aliphatic Index 94.83

Aromaticity 0.0787

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7611.45

LogP -82.11

H-bond Donors 263.0

H-bond Acceptors 256.0

Rotatable Bonds 614.0

Heavy Atoms 1379.0

Ring Count 39.0

Amide Bonds 191.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0138055 VERIFIED: NO

Provenance & Taxonomy

OrganismCalonectris borealis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria