Peptide Database

Peptide NameIbritumomab

Function Ontology

Anticancer

Standard StatusStandard

Sequence Length242 amino acids

Chemical FormulaC1162H1777N295O356S11

DescriptionStandard

        QAYLQQSGAELVRPGASVKMSCKASGYTFTSYNMHWVKQTPRQGLEWIGAIYPGNGDTSYNQKFKGKATLTVDKSSSTAYMQLSSLTSEDSAVYFCARVVYYSNSYWYFDVWGTGTTVTVSAPSVYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAHPASSTKVDKKIEPRGPTIKPCPPCKCPAPNLLGGPSVFI
    

Molecular Weight25928.02 Da

Isoelectric Point (pI)8.71

Net Charge (pH 7.0)4.94

Net Charge (pH 7.4) 4.41

Charge Density (pH 7.0) 0.0204

GRAVY Index-0.12

Hydrophobic Moment 0.59

Boman Index0.12

Instability Index41.95

Aliphatic Index 68.02

Aromaticity 0.1116

Extinction Coeff. Reduced 53860.00

Extinction Coeff. Oxidized 54360.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0289516 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]; Cricetulus griseus [Animal]

FamilyMonoclonal antibody

Tax ID10090;10029

Structure & Mods

Configlinear multidomain protein biologic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer Monoclonal antibody

Half-Life0.8 h (mammalian reticulocytes, in vitro)

PaperPubMed-linked source references: PMID:16810345; PMID:20383346; PMID:28269762; PMID:26758269; PMID:22045523; PMID:21355777; PMID:21225019; PMID:21225012; PMID:20094643 PMID16810345;20383346;28269762;26758269;22045523;21355777;21225019;21225012;20094643 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16810345/ PatentCA2149329