Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length141 amino acids

Chemical FormulaC690H1112N196O189S4

DescriptionStandard

        PAALPVAHQPMLLLAVTDFVANSAAFTYFTAGALRRNISSNMLPRRFPLQLRTKSLGTFSPRLQELYPDQPMELHLSARRQPLLSCRPDALHGALFGSAEAFVVLPNATRLPAFLLNIDANVTGKPTITKNRVGGTVKLTG
    

Molecular Weight15305.67 Da

Isoelectric Point (pI)10.86

Net Charge (pH 7.0)8.22

Net Charge (pH 7.4) 7.98

Charge Density (pH 7.0) 0.0583

GRAVY Index0.07

Hydrophobic Moment 0.57

Boman Index0.08

Instability Index52.68

Aliphatic Index 97.66

Aromaticity 0.0709

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6091.88

LogP -60.03

H-bond Donors 211.0

H-bond Acceptors 204.0

Rotatable Bonds 488.0

Heavy Atoms 1079.0

Ring Count 26.0

Amide Bonds 152.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0094351 VERIFIED: NO

Provenance & Taxonomy

OrganismChordeiles acutipennis (Lesser nighthawk) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria