‹ ›
MYP_142262
← PREVIOUS NEXT → BACK
Basic Information
USCL-PCat1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV-2
Binding / Molecular interaction ▸ Metal-binding / iron acquisition ▸ Siderophore
Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition
Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
not Standard
4 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XXXX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0036796 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
CH3(CH2)8CO
Amidation
Ornithine at 1,2,3,4; Ornithine; Contains unresolved X placeholder residue(s)
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa MTCC 2295
25 μg/mL
MIC
PaperSystematic Study of Non-Natural Short Cationic Lipopeptides as Novel Broad-Spectrum Antimicrobial Agents; DOI:10.1111/cbdd.12182 PMID23819506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23819506/
RECORD: Rec_0039493 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
C16
Amidation
Dab = L-diaminobutyric acid at 1,2,3,4; Dab = L-diaminobutyric acid; Contains unresolved X placeholder residue(s)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
methicillin-susceptible Staphylococcus epidermidis CANWARD-2008 81388
4 μg/mL
MIC
PaperStructure-activity relationships in ultrashort cationic lipopeptides: the effects of amino acid ring constraint on antibacterial activity; DOI:10.1007/s00726-014-1806-z PMID25069750 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25069750/
RECORD: Rec_0039746 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
C16
Amidation
Dab = L-diaminobutyric acid, X = HSe = L-homoserine at 1,4; unspecified non-canonical residue at 2,3; Dab = L-diaminobutyric acid, X = HSe = L-homoserine; Contains unresolved X placeholder residue(s)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa CANWARD-2011 96846
32 μg/mL
MIC
PaperStructure-activity relationships in ultrashort cationic lipopeptides: the effects of amino acid ring constraint on antibacterial activity; DOI:10.1007/s00726-014-1806-z PMID25069750 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25069750/
RECORD: Rec_0039950 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
C16
Amidation
Dab = L-diaminobutyric acid at 1,2,3,4; Dab = L-diaminobutyric acid; Contains unresolved X placeholder residue(s)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis ATCC 29212
8 μg/mL
MIC
PaperStructure-activity relationships in ultrashort cationic lipopeptides: the effects of amino acid ring constraint on antibacterial activity; DOI:10.1007/s00726-014-1806-z PMID25069750 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25069750/
RECORD: Rec_0043517 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
C16
Amidation
Pcat = L-4R-aminoproline, B = PHyp = L-4R-hydroxyproline at 1,4; non-canonical residue code at 2,3; Pcat = L-4R-aminoproline, B = PHyp = L-4R-hydroxyproline; Contains unresolved X placeholder residue(s)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa CAN-ICU 62308
128 μg/mL
MIC
PaperStructure-activity relationships in ultrashort cationic lipopeptides: the effects of amino acid ring constraint on antibacterial activity; DOI:10.1007/s00726-014-1806-z PMID25069750 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25069750/
FIRST PREV 1 2 3 4 5 6 ... 32 NEXT LAST
Showing 5 records · Page 4 of 32