MYP_142262
Basic Information
USCL-PCat1
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-negative
Antimicrobial Antibacterial Anti-Gram-positive
Antimicrobial Antifungal
Antiparasitic Antimalarial
Antiparasitic Antiprotozoal Antimalarial Anti-Plasmodium
Antiparasitic General antiparasitic Antiparasitic
Antiviral
Antiviral Anti-Coronavirus Anti-SARS-CoV-2
Binding / Molecular interaction Metal-binding / iron acquisition Siderophore
Enzyme modulation Enzyme inhibition Protease inhibition
Membrane / Ion-channel modulation Sodium channel modulation Sodium channel inhibitor
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Venom / Toxin General toxin Toxic
not Standard
4 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XXXX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0370331 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
C16
Amidation
Pcat = L-4R-aminoproline, B = PHyp = L-4R-hydroxyproline at 1,4; non-canonical residue code at 2,3; Pcat = L-4R-aminoproline, B = PHyp = L-4R-hydroxyproline
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
MSSE CANWARD-2008 81388
32
RECORD: Rec_0370686 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
unknown
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Non-proteinogenic/modified monomers: NMe-Ala; 1y2; 1y3; 1xy
Bio-Activity Profile
-
RECORD: Rec_0373872 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Oligo-acyl-lysyl
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
A=amino; l=lauric acid,alK=aminolauryl-lysine
Bio-Activity Profile
Antimicrobial Antimalarial Antiparasitic
Plasmodium falciparum W2
1.59 μM
IC50; [3H] Hypoxanthine incorporation assay
RECORD: Rec_0375514 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
C16
Amidation
Pcat = L-4R-aminoproline, B = PHyp = L-4R-hydroxyproline at 1,4; non-canonical residue code at 2,3; Pcat = L-4R-aminoproline, B = PHyp = L-4R-hydroxyproline
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
S. pneumoniae ATCC 49619
128
RECORD: Rec_0375912 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
C16
Amidation
Dab = L-diaminobutyric acid, X = HSe = L-homoserine at 1,4; unspecified non-canonical residue at 2,3; Dab = L-diaminobutyric acid, X = HSe = L-homoserine
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterococcus faecium ATCC 27270
16
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