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MYP_142262
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Basic Information
USCL-PCat1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV-2
Binding / Molecular interaction ▸ Metal-binding / iron acquisition ▸ Siderophore
Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition
Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
not Standard
4 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XXXX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0301859 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
CH3(CH2)12CO
Amidation
Ornithine at 1,2,3,4; Ornithine
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Aspergillus fumigatus ATCC 42203
3.1 μg/mL
PMID23819506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23819506/
RECORD: Rec_0304574 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
C16
Amidation
Pcat = L-4R-aminoproline at 1,2,3,4; Pcat = L-4R-aminoproline
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli CAN-ICU 61714
32
PMID25069750 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25069750/
RECORD: Rec_0305176 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cyclic peptide
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiparasitic Antimalarial
Plasmodium falciparum W2 Indochina
6 μM
IC50; Fluorimetry (PicoGreen)
PMID17441769 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17441769/
RECORD: Rec_0305901 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
unknown
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Non-proteinogenic/modified monomers: NMe-Ala; Chg; 1y4; 1y5
Bio-Activity Profile
-
RECORD: Rec_0306169 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
C16
Amidation
Dab = L-diaminobutyric acid at 1,2,3,4; Dab = L-diaminobutyric acid
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae ATCC 13883
16
PMID25069750 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25069750/
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