Peptide Database

Peptide NameEnterocin AS-48 (46-70)[G2W,A21I,I23A]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC141H234N40O32

DescriptionStandard

        AWRESIKAYLKKEIKKKGKRIVAAW
    

Molecular Weight3001.62 Da

Isoelectric Point (pI)10.46

Net Charge (pH 7.0)6.79

Net Charge (pH 7.4) 6.59

Charge Density (pH 7.0) 0.2717

GRAVY Index-0.76

Hydrophobic Moment 0.78

Boman Index-0.24

Instability Index17.67

Aliphatic Index 90.00

Aromaticity 0.1200

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1214.30

LogP -5.87

H-bond Donors 45.0

H-bond Acceptors 39.0

Rotatable Bonds 107.0

Heavy Atoms 213.0

Ring Count 5.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0215894 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

TargetSheep erythrocytes (14.4% Hemolysis at >32 μM

Activity32 μM

MethodHemolysis

RECORD: Rec_0353617 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli BL21

Activity4 μM

MethodMIC