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MYP_142151
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Basic Information
Cecropin Sb, SibaCec
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
34 amino acids
C152H276N48O41
Standard
Sequence
GKLTKDKLKRGAKKALNVASKVAPIVAAGASIAR
Physicochemical Analysis
3432.11 Da
11.30
7.75
7.54
0.2281
-0.03
0.76
-0.06
-0.01
106.47
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1461.85
-15.70
52.0
49.0
122.0
241.0
1.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0104180 VERIFIED: NO
Provenance & Taxonomy
Simulium bannaense [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Streptococcus dysgalactiae et al, Escherichia coli et al
RECORD: Rec_0153370 VERIFIED: YES
Provenance & Taxonomy
Simulium bannaense [Animal]
SibaCec
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperParasit Vectors. 2015 Oct 24;8(1):561. | https://www.ncbi.nlm.nih.gov/pubmed/26497304 PMID26497304 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26497304/
RECORD: Rec_0193147 VERIFIED: YES
Provenance & Taxonomy
Simulium bannaense [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes (3% Hemolysis at 200 microg/ml
200 μg/mL
Hemolysis
PMID26497304 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26497304/
RECORD: Rec_0276770 VERIFIED: YES
Provenance & Taxonomy
Simulium bannaense [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory
Gram+ Staphylococcus aureus ATCC 6538, Bacillus subtilis ATCC 6633, and Micrococcus luteus ATCC 4698
14.5-43.7 μM
MIC
PaperA cecropin-like antimicrobial peptide with anti-inflammatory activity from the black fly salivary glands
RECORD: Rec_0330081 VERIFIED: YES
Provenance & Taxonomy
Simulium bannaense [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Salmonella enterica subsp. enterica serovar Typhimurium ATCC 14028
2.33 μM
MIC
PMID26497304 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26497304/
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