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MYP_142151
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Basic Information
Cecropin Sb, SibaCec
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
34 amino acids
C152H276N48O41
Standard
Sequence
GKLTKDKLKRGAKKALNVASKVAPIVAAGASIAR
Physicochemical Analysis
3432.11 Da
11.30
7.75
7.54
0.2281
-0.03
0.76
-0.06
-0.01
106.47
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1461.85
-15.70
52.0
49.0
122.0
241.0
1.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0008930 VERIFIED: YES
Provenance & Taxonomy
Simulium bannaense [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Micrococcus luteus ATCC 4698
14.56 μM
MIC
PMID26497304 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26497304/
RECORD: Rec_0030110 VERIFIED: YES
Provenance & Taxonomy
Simulium bannaense [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Acinetobacter baumannii ATCC 17978
2.33 μM
MIC
PMID26497304 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26497304/
RECORD: Rec_0060155 VERIFIED: YES
Provenance & Taxonomy
Simulium bannaense [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis ATCC 6633
29.13 μM
MIC
PMID26497304 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26497304/
RECORD: Rec_0066469 VERIFIED: YES
Provenance & Taxonomy
Simulium bannaense [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli 1
1.45 μM
MIC
PMID26497304 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26497304/
RECORD: Rec_0087845 VERIFIED: YES
Provenance & Taxonomy
Simulium bannaense [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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