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MYP_142128
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Basic Information
Astacidin PcAst-1a
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
18 amino acids
C98H143N31O26
Standard
Sequence
SNGYRPAYRPAYRPSYRP
Physicochemical Analysis
2171.38 Da
10.42
3.46
3.24
0.1920
-1.75
0.72
-0.45
33.70
11.11
0.2222
5960.00
5960.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
934.93
-9.96
34.0
30.0
59.0
155.0
8.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0125093 VERIFIED: YES
Provenance & Taxonomy
Procambarus clarkii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 29213
32 μM
MIC
PMID31884202 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31884202/
RECORD: Rec_0146692 VERIFIED: YES
Provenance & Taxonomy
Procambarus clarkii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
32 μM
MIC
PMID31884202 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31884202/
RECORD: Rec_0162067 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
T24
100 μM
IC50
PaperPubMed PMID: 31884202 PMID31884202 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31884202/
RECORD: Rec_0206853 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
MEC-1 (Not active up to 100 μM)
PaperPubMed PMID: 31884202 PMID31884202 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31884202/
RECORD: Rec_0212782 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 31884202 PMID31884202 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31884202/
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