‹ ›
MYP_142095
← PREVIOUS NEXT → BACK
Basic Information
Hymenochirin-4B
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
28 amino acids
C133H232N34O35
Standard
Sequence
IKIPAFVKDTLKKVAKGVISAVAGALTQ
Physicochemical Analysis
2867.47 Da
10.18
3.76
3.55
0.1341
0.66
0.69
0.23
-11.79
128.93
0.0357
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1111.41
-8.41
38.0
39.0
98.0
202.0
2.0
28.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0040043 VERIFIED: YES
Provenance & Taxonomy
Hymenochirus boettgeri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
L. salivarius DSM20554 [
250 μg/mL
MBC
PMID31102497 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31102497/
RECORD: Rec_0046652 VERIFIED: YES
Provenance & Taxonomy
Hymenochirus boettgeri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
L. plantarum WCFS1 [
250 μg/mL
MBC
PMID31102497 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31102497/
RECORD: Rec_0064273 VERIFIED: YES
Provenance & Taxonomy
Hymenochirus boettgeri [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
PMID22497805 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22497805/
RECORD: Rec_0068095 VERIFIED: YES
Provenance & Taxonomy
Hymenochirus boettgeri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa Sens 2 ATCC 27853 [
32 μg/mL
MBC
PMID31102497 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31102497/
RECORD: Rec_0077901 VERIFIED: YES
Provenance & Taxonomy
Hymenochirus boettgeri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
FIRST PREV 1 2 3 4 ... 13 NEXT LAST
Showing 5 records on this page · Page 2 of 13