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MYP_142090
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Basic Information
alpha-Atrial natriuretic peptide [5-28]
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Reproductive biology ▸ Reproductive modulation
Standard
24 amino acids
C107H167N35O34S2
Standard
Sequence
SSCFGGRIDRIGAQSGLGCNSFRY
Physicochemical Analysis
2551.81 Da
8.94
1.44
1.20
0.0600
-0.22
0.60
-0.03
44.82
52.92
0.1250
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1142.95
-16.47
44.0
38.0
84.0
178.0
3.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0058569 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
10116
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-19
Bio-Activity Profile
Neuropeptide
RECORD: Rec_0081750 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Atriopeptin
10116
Structure & Mods
disulfide-constrained peptide [Cyclic]
noncanonical stereochemical modification [Modified]
3-19
2:Phosphoserine
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Reproductive regulator Growth regulation Development regulation Myotropic Receptor modulation ACE inhibitory
Experimental: 2.5 minute; /150 seconds; Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Atriopeptin-3 (Rattus norvegicus): PMID 3160114##6239307 PMID3160114;6239307 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3160114/
RECORD: Rec_0193142 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
RECORD: Rec_0237094 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Atriopeptin
10116
Structure & Mods
disulfide-constrained peptide [Cyclic]
noncanonical stereochemical modification [Modified]
3-19
2:Phosphoserine
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Reproductive regulator Growth regulation Development regulation Myotropic Receptor modulation ACE inhibitory
adipose tissue
Experimental: 2.5 minute; /150 seconds; Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Atriopeptin-3 (Rattus norvegicus): PMID 3160114##6239307 PMID3160114;6239307 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3160114/
RECORD: Rec_0304092 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
Natriuretic peptide
10116
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-19
Bio-Activity Profile
Hormone Cardiovascular
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